کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1317205 | 976514 | 2007 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis, crystal structures and cytotoxicities of some transition metal complexes with N-[2-{(pyridin-2-ylmethylidene)amino}ethyl]acetamide
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی معدنی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis, crystal structures and cytotoxicities of some transition metal complexes with N-[2-{(pyridin-2-ylmethylidene)amino}ethyl]acetamide Synthesis, crystal structures and cytotoxicities of some transition metal complexes with N-[2-{(pyridin-2-ylmethylidene)amino}ethyl]acetamide](/preview/png/1317205.png)
چکیده انگلیسی
The synthesis and spectroscopic (IR, 1H and 13C NMR) characterization of new complexes of Pt(II), Pd(II), Cu(II), and Hg(II) with the Schiff base ligand MeCONHCH2CH2NCHPy (L) (Py = pyridine) are reported, together with studies on the cytotoxicities of these complexes, L and [ReBr(CO)3(L)] against human leukemia (MOLT-4), breast cancer (MCF-7) and Chang Liver (non-cancerous) cells. The crystal structures of [Pt(L)Cl2] (2), [Cu(L)Cl2] (4) and [Hg(L)Cl2]2 (5) are also reported. Of the complexes studied, [Cu(L)Cl2] (4) was identified as the most cytotoxic active derivative against cells of neoplastic origin (MOLT-4, and MCF-7), while having low toxicity on cells of benign origin (Chang Liver).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Inorganic Biochemistry - Volume 101, Issue 2, February 2007, Pages 321–328
Journal: Journal of Inorganic Biochemistry - Volume 101, Issue 2, February 2007, Pages 321–328
نویسندگان
Xinxin Zhao, Peter Peng-Foo Lee, Yaw-Kai Yan, Chit-Kay Chu,