کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1321557 | 1499894 | 2013 | 8 صفحه PDF | دانلود رایگان |
• Synthesis of complex polycyclic heterocycles in accessible by other methods.
• Synthesis involves 1,3-dipolar cycloaddition reaction as the key step.
• It is a one pot multi component reaction with azomethine ylide as a dipole.
An expedient one-pot four component ultrasonic assisted synthesis of novel ferrocene grafted spiro-pyrrolidine heterocycles via [3 + 2]-cycloaddition of azomethine ylides is described. The protocol provides a mild reaction conditions, high yield of product in short reaction time, high regioselectivity, operational simplicity and applicable to a wide variety of ferrocene derived dipolarophiles for the efficient synthesis of ferrocene appended heterocycles. The structures of cycloadducts were confirmed by spectroscopic analysis. X-ray analysis of the products adds conclusive support to the proposed structure.
A facile one-pot four component ultrasonic assisted synthesis of novel ferrocene grafted spiro-indenoquinoxaline pyrrolidines via [3 + 2]-cycloaddition of azomethine ylides is described.Figure optionsDownload as PowerPoint slide
Journal: Journal of Organometallic Chemistry - Volumes 745–746, 15 November 2013, Pages 409–416