Mechanistic studies on the Shilov system: A retrospective

• We recall our encounters with, and inspiration by, Alex Shilov.
• Studies on the Shilov system lead to a global mechanism for alkane hydroxylation.
• Further studies on model Pt complexes provide finer mechanistic details.
• We examine implications for potential practical applications.

Following a brief account of our personal encounters with Alex Shilov, we summarize our 20+ years work on the mechanism of the Shilov system and related C–H activation chemistry.

Global mechanism and overall stoichiometry of the Shilov system for alkane hydroxylation.Figure optionsDownload as PowerPoint slide