کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1322358 | 977203 | 2011 | 10 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Palladium-catalyzed 1,3-butadiene telomerization with methanol. Improved catalyst performance using bis-o-methoxy substituted triarylphosphines Palladium-catalyzed 1,3-butadiene telomerization with methanol. Improved catalyst performance using bis-o-methoxy substituted triarylphosphines](/preview/png/1322358.png)
New, improved phosphine ligands for palladium-catalyzed butadiene telomerization with methanol have been discovered. Using high throughput experimentation and an Electrospray Ionization-Mass Spectrometry (ESI-MS) investigation of telomerization catalysts solutions, we have identified phosphines of the type P(C6H4-2-OMe)2(C6H5−n(X)n), where X is an electron-withdrawing group, as high selectivity, high activity phosphine ligands for butadiene telomerization with methanol to 1-methoxy-2,7-octadiene (MOD-1). These ligands were designed to mitigate anaerobic oxidation of phosphines by alkylation which was shown by Electrospray Ionization-Mass Spectrometry (ESI-MS) studies to correlate with catalyst death and palladium precipitation in working telomerization catalyst solutions. The best phosphine-promoted catalysts achieve selectivities to desired 1-methoxy-2,7-octadiene of 94% at high butadiene conversion, significantly improved over those achieved commercially by triphenylphosphine.
New, improved phosphine ligands for palladium-catalyzed butadiene telomerization with methanol have been discovered. Using high-throughput experimentation and an Electrospray Ionization-Mass Spectrometry (ESI-MS) investigation of telomerization catalysts solutions, we have identified phosphines of the type P(C6H4-2-OMe)2(C6H5-n(X)n), where X is an electron withdrawing group, as high-selectivity, high activity phosphine ligands for 1,3-butadiene telomerization with methanol to 1-methoxy-2,7-octadiene.Figure optionsDownload as PowerPoint slideHighlights
► New, improved phosphine ligands for palladium-catalyzed butadiene telomerization with methanol have been discovered.
► These ligands were designed to mitigate anaerobic oxidation of phosphines by alkylation which was shown by Electrospray Ionization-Mass Spectrometry (ESI-MS) studies to correlate with catalyst death and palladium precipitation.
► The best phosphine-promoted catalysts achieve selectivities to desired 1-methoxy-2,7-octadiene of 94% at high butadiene conversion, significantly improved over those achieved commercially by triphenylphosphine.
Journal: Journal of Organometallic Chemistry - Volume 696, Issue 8, 15 April 2011, Pages 1677–1686