Asymmetric activation of the tropos biphenyldiamidophosphite moiety: Synthesis and complexation to rhodium of a deoxycholic acid derived diamidophosphite

• The asymmetric activation of the flexible biphenyldiamidophosphite moiety is reported.
• High diastereomeric prevalence is obtained in the formation of Rh-complexes.
• Both monosubstituted and disubstituted Rh-complexes can be obtained.

A tropos deoxcholic acid derived diamidophosphite was synthesised starting from deoxycholic acid and N,N′-dimethyl-2,2′-diamino-1,1′biphenyl and its stereodinamic characteristics were assessed by VT-NMR spectroscopy. The capability of the diamidophosphite to act as Rh-ligand was investigated in the formation of ionic as well as covalent Rh-complexes. The stereodinamic properties of these complexes were studied by VT-NMR spectroscopy.

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