Suzuki cross-coupling catalyzed by palladium (II) complexes bearing 1-aryl-3,4,5,6-tetrahydropyrimidine ligands

A novel highly efficient monodentate imine palladium catalyst system has been tested for Suzuki cross-coupling reaction. Under the standard conditions, a series of aryl halides, including phenyl iodide, aryl bromides and phenyl chloride, were coupled with phenylboronic or 1-naphthylboronic acid, producing the corresponding biaryls in good to excellent yields. High-resolution transmission electron microscopy (HR-TEM) study of the recycled catalyst showed the formation of palladium nano particles in the catalytic system.

A novel highly efficient monodentate imine palladium catalyst has been tested for Suzuki cross-coupling reaction. Under the standard conditions, a series of aryl halides coupled with phenylboronic or 1-naphthylboronic acid efficiently. HR-TEM study of the recycled catalyst showed the formation of palladium nano particles in the catalytic system.Figure optionsDownload as PowerPoint slideHighlights
► An efficient imine palladium catalyst for Suzuki cross-coupling was presented.
► Standard conditions: t-BuOK as base, 1:1 mixture of DMF/H2O as solvent, 100 °C.
► It showed high activity for the cross-coupling of ArX (X = Cl, Br, I) with ArB(OH)2.
► HR-TEM showed the formation of palladium nano particles in the catalytic system.