کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1323428 1499878 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis and characterization of novel chiral bidentate P,N-containing ligands and ruthenium(II) complex. The application in asymmetric transfer hydrogenation of ketones
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Synthesis and characterization of novel chiral bidentate P,N-containing ligands and ruthenium(II) complex. The application in asymmetric transfer hydrogenation of ketones
چکیده انگلیسی


• Novel chiral bidentate P,N-containing ligands were synthesized and characterized.
• Novel chiral Ru(II) complex was successfully prepared and characterized by X-ray diffraction studies.
• ATH of various ketones catalyzed by chiral Ru(II) complex proceeded smoothly under mild conditions.

Novel chiral bidentate P,N-containing ligands have been easily synthesized by Schiff-base condensation of o-(diphenylphosphino)benzaldehyde and modified chiral diamine, (R,R)-2-(2,5-dimethyl-pyrrol-1-yl)-cyclohexylamine, further reduction with NaBH4. The chiral ruthenium(II) complex could be successfully prepared from the reaction between chiral bidentate aminophosphine ligand and RuCl2(PPh3)3. The chiral bidentate P,N-containing ligands and ruthenium(II) complex were fully characterized by NMR, IR, HRMS and single-crystal X-ray diffraction studies. In the presence of KOH, the asymmetric transfer hydrogenation (ATH) of various ketones catalyzed by the chiral ruthenium(II) complex proceeded smoothly under mild conditions, affording corresponding chiral secondary alcohols with up to 99% conversion and up to 60% ee. Additive such as NH4I was found to be helpful to promoting the enantioselectivity.

Novel chiral bidentate P,N-containing ligands and corresponding five-coordinated chiral ruthenium(II) complex have been successfully synthesized and characterized. The asymmetric transfer hydrogenation (ATH) of various ketones catalyzed by the chiral ruthenium(II) complex proceeded smoothly with up to 99% conversion and up to 60% ee.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Organometallic Chemistry - Volume 762, 15 July 2014, Pages 34–39
نویسندگان
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