کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1323634 | 1499886 | 2014 | 6 صفحه PDF | دانلود رایگان |
• Three different synthetic routes to 2-silyl substituted 1,3-dienes are presented.
• Hydrosilylation of enynes yields mixtures of regioisomers.
• Grignard chemistry is the best synthetic route when 2-halo-1,3-dienes are available.
A number of 2-silicon substituted 1,3-dienes have been prepared by one of three routes: 1) Reactions of 1,3-dienyl Grignard reagents with silyl electrophiles or silyl Grignard reagents with 1,3-dienyl electrophiles; 2) Hydrosilylation of enynes; 3) Enyne cross metathesis. The strengths and limitations of each preparative method are discussed.
A number of 1,3-dienes have been prepared by: 1) Reactions of 1,3-dienyl Grignard reagents with silyl electrophiles or silyl Grignard reagents with 1,3-dienyl electrophiles; 2) Hydrosilylation of enynes; or 3) Enyne cross metathesis. Use of Grignard chemistry where possible is preferred over enyne hydrosilyation or cross metathesis.Figure optionsDownload as PowerPoint slide
Journal: Journal of Organometallic Chemistry - Volume 754, 15 March 2014, Pages 88–93