Tris(polymethoxyphenyl)bismuth derivatives: Synthesis and reactivity

Tris-(polymethoxyphenyl)bismuth diacetate and dichloride derivatives react with C-nucleophiles in basic medium, as well as with N- and O-nucleophiles under copper catalysis to give good to high yields of the corresponding C-, N- and O-arylation products.

A range of new tris-(polymethoxyphenyl)bismuthanes, tris-(polymethoxyphenyl)bismuth diacetates and dichlorides have been synthesized. These compounds are useful reagents for the transfer of aryl fragments with electron-donating substituents in C-arylation reactions under basic conditions, as well for the copper-catalyzed N- and O-arylation reactions.Figure optionsDownload as PowerPoint slide