New nitrochromenylmethylidene-containing ruthenium metathesis catalyst

New Hoveyda-Grubbs type catalyst containing nitrochromenyl ligand is reported herein. The catalyst was tested in model RCM, CM and enyne reactions. Its activity was compared with that of commercially available complexes and with literature data for Grela catalyst. New catalyst appeared to be fast initiating, but less stable than other catalysts.

A new Hoveyda-Grubbs type metathesis catalyst containing nitrochromene moiety was synthesized. The complex was tested in CM, RCM and enyne reactions as well as its activity was compared with that of commercially available catalysts.Figure optionsDownload as PowerPoint slideHighlights
► New catalyst was active in RCM (leading to di- or tri-substituted cycloalkenes), CM and enyne reactions.
► The catalyst rapidly initiated metathetic transformations, but in the progress of reaction it underwent to decomposition.
► The complex was storable and resistant to oxygen and moisture.