Regio- and stereoselective synthesis of tetrasubstituted allylic alcohols by three-component reaction of acetylenic sulfone, dialkylzinc, and aldehyde

(Z)-Tetrasubstituted allylic alcohols bearing sulfonyl group were synthesized regio- and stereoselectively by alkylzincation of acetylenic sulfone followed by addition to aldehyde.

(Z)-Tetrasubstituted allylic alcohols bearing sulfonyl group were synthesized regio- and stereoselectively by alkylzincation of acetylenic sulfone followed by addition to aldehyde.Figure optionsDownload as PowerPoint slide