کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1324862 | 977358 | 2011 | 6 صفحه PDF | دانلود رایگان |
A series of bidentate sulfonamide alcohol ligands with varying steric and electronic properties was synthesized. The titanium and tantalum complexes of these ligands, prepared in situ from either Ti(NMe2)4 or Ta(NMe2)5, were used as catalysts for the asymmetric hydroamination of 6-methyl-hepta-4,5-dienylamine, giving exclusively the α-vinylpyrrolidine product. The titanium derived catalysts gave products with low stereoselectivity, up to 11%ee favoring (+)-2-(2-methyl-propenyl)-pyrrolidine, while the tantalum derived catalysts gave products with higher and opposite stereoselectivity, up to 34%ee favoring (−)-2-(2-methyl-propenyl)-pyrrolidine.
Titanium and Tantalum complexes of bidentate sulfonamide alcohol ligands catalyze the asymmetric hydroamination of aminoallenes, giving exclusively the α-vinylpyrrolidine product in up to 34%ee.Figure optionsDownload as PowerPoint slide
Journal: Journal of Organometallic Chemistry - Volume 696, Issue 1, 1 January 2011, Pages 81–86