Fe(Cp)2PF6: An efficient catalyst for cyanosilylation of carbonyl compounds under solvent free condition

An efficient method for the addition of trimethylsilyl cyanide (TMSCN) to various aldehydes and ketones has been described using Fe(Cp)2PF6 (2.5 mol%) as a catalyst under solvent free condition. Excellent yields of trimethylsilylether of cyanohydrin up to (94%) was achieved within 10 min.

The addition of trimethylsilyl cyanide (TMSCN) to various aldehydes and ketones catalyzed by 2.5 mol% Fe(Cp)2PF6 as a catalyst was carried out under solvent free condition. Excellent yields of trimethylsilylether of cyanohydrin (65–94%) was achieved within 10 min.Figure optionsDownload as PowerPoint slide