کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1325329 | 977379 | 2011 | 6 صفحه PDF | دانلود رایگان |

In this study, crystalline and chirally stable carboxyl-protected and novel unprotected N-ferrocenoyl amino acid derivatives of Ser, Cys, Ala, Phe, Trp, Asp and Asn have been prepared. These amino acids undergo substitution reaction with 1-(ferrocenylcarbonyl)-1H-benzotriazole, 1, in partially aqueous media under microwave irradiation.
N-Ferrocenoylbenzotriazole mediated preparation of carboxy-protected and unprotected ferrocenoylamidoamino acids were prepared under microwave irradiation.Figure optionsDownload as PowerPoint slideHighlights
► Crystalline, chirally stable carboxy-protected and novel unprotected N-ferrocenoyl amino acid derivatives were prepared.
► During preparation of target molecules, 1-(ferrocenylcarbonyl)-1H-benzotriazole was used as a starting material under MW irradiation.
► Prepared unprotected N-ferrocenoylamidoamino acid can be used for peptide coupling with different amino acids, without any protection and deprotection process.
Journal: Journal of Organometallic Chemistry - Volume 696, Issue 13, 1 July 2011, Pages 2543–2548