کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1325329 977379 2011 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
N-acylbenzotriazole mediated microwave assisted synthesis of protected and novel unprotected ferrocenoylamidoamino acids
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
N-acylbenzotriazole mediated microwave assisted synthesis of protected and novel unprotected ferrocenoylamidoamino acids
چکیده انگلیسی

In this study, crystalline and chirally stable carboxyl-protected and novel unprotected N-ferrocenoyl amino acid derivatives of Ser, Cys, Ala, Phe, Trp, Asp and Asn have been prepared. These amino acids undergo substitution reaction with 1-(ferrocenylcarbonyl)-1H-benzotriazole, 1, in partially aqueous media under microwave irradiation.

N-Ferrocenoylbenzotriazole mediated preparation of carboxy-protected and unprotected ferrocenoylamidoamino acids were prepared under microwave irradiation.Figure optionsDownload as PowerPoint slideHighlights
► Crystalline, chirally stable carboxy-protected and novel unprotected N-ferrocenoyl amino acid derivatives were prepared.
► During preparation of target molecules, 1-(ferrocenylcarbonyl)-1H-benzotriazole was used as a starting material under MW irradiation.
► Prepared unprotected N-ferrocenoylamidoamino acid can be used for peptide coupling with different amino acids, without any protection and deprotection process.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Organometallic Chemistry - Volume 696, Issue 13, 1 July 2011, Pages 2543–2548
نویسندگان
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