کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1325370 | 1499870 | 2014 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Amide synthesis from alcohols and amines catalyzed by a RuII–N-heterocyclic carbene (NHC)–carbonyl complex Amide synthesis from alcohols and amines catalyzed by a RuII–N-heterocyclic carbene (NHC)–carbonyl complex](/preview/png/1325370.png)
• Oxidative route to Ru–N-heterocyclic carbene complex from metal–metal bonded precursor.
• Catalyst for direct amidation from alcohols and amines.
• Phosphine-free, acceptorless amidation catalyst at low catalyst loading.
• A RuII-dihydride/Ru0 sequence is proposed in the catalytic cycle.
Treatment of [Ru2(CO)4(CH3CN)6](BF4)2 with 3-methyl-1-(pyridin-2-yl)-imidazolium bromide in the presence of tetrabutylammonium bromide at room temperature in dichloromethane affords a RuII–N-heterocyclic carbene–carbonyl complex [Ru(py-NHC)(CO)2Br2] (1). Catalyst 1 displays diverse substrate scope for phosphine-free acceptorless coupling between alcohols and amines to amides at low catalyst loading. A RuII-dihydride/Ru0 sequence is proposed in the catalytic cycle.
Ru(II) catalyst catalyzes phosphine-free acceptor-less coupling between alcohols and amines to amides at low catalyst loading.Figure optionsDownload as PowerPoint slide
Journal: Journal of Organometallic Chemistry - Volume 771, 15 November 2014, Pages 124–130