کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1326083 | 1499953 | 2005 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: [6 + 3] Cycloaddition of Fischer aminocarbene complexes: An efficient annulation of fulvenes to indene derivatives [6 + 3] Cycloaddition of Fischer aminocarbene complexes: An efficient annulation of fulvenes to indene derivatives](/preview/png/1326083.png)
Alkenyl(amino)carbene chromium(0) complexes 1 undergo regioselective [6 + 3] cycloaddition to pentafulvenes 2, affording substituted dihydroindenes 5a–d and indene 6. In the case of 6,6-dimethylpentafulvene 2a dihydroindene chromium complexes 4a–c were also isolated. Isopropylfulvene 2b similarly produces 5d or, under oxidative reaction conditions, the indene 6. The reaction involves: (i) 1,2-nucleophilic addition of fulvene to the carbene carbon, (ii) [1,2]-Cr(CO)5 migration, (iii) either metal–indene coordination or reductive metal elimination/aromatization.
Fischer alkenyl aminocarbene complexes smoothly undergo a [6 + 3] cyclization reaction to fulvenes. This process allows to access 6,7-dihydro-4-amino-5H-indene and 7-amino-1H-indene derivatives.Figure optionsDownload as PowerPoint slide
Journal: Journal of Organometallic Chemistry - Volume 690, Issues 24–25, 1 December 2005, Pages 5696–5700