Thermal and photochemical reactions of Fischer carbene complexes with trialkylsilyl-substituted alkynes

Thermal reaction of Fischer carbene complexes with triisopropylsilyl (TIPS) substituted alkynes in benzene afforded TIPS-substituted vinylketenes or 2-TIPS-substituted cyclobutenones as major products while photochemical reaction of Fischer carbene complexes with trimethylsilyl (TMS) substituted alkynes in acetonitrile afforded 3-TMS-substituted cyclobutenones.

Thermal reaction of Fischer carbene complexes with triisopropylsilyl (TIPS) substituted alkynes in benzene afforded TIPS-vinylketenes or 2-TIPS-substituted cyclobutenones as major products while photochemical reaction of Fischer carbene complexes with trimethylsilyl (TMS) substituted alkynes in acetonitrile afforded 3-TMS-substituted cyclobutenones.Figure optionsDownload as PowerPoint slide