کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1326855 | 977447 | 2007 | 9 صفحه PDF | دانلود رایگان |
Carboxy-terminated polyvinylpyrrolidin-2-one (PVP) has been used as a new water-soluble and biocompatible polymeric support for a series of ferrocene labeled amino acid and peptide nucleic acid (PNA) monomer derivatives 4–7. The organometallic polymer-conjugates thus obtained are new and potentially useful as water-soluble electrochemically active probes for biomolecules. In view of such application, their electrochemical activity has been evaluated and has proved very high notwithstanding the complexity and bulkiness of the molecule, affording detection limits down to 10−8 M in the aqueous medium.
End-carboxy functionalized poly(N-vinylpyrrolidin-2-one) (PVP) has been used as new water-soluble and biocompatible polymeric support for a series of ferrocene labeled amino acid and PNA monomer derivatives. The organometallic polymer-conjugates thus obtained are new and potentially useful as water-soluble electrochemically active probes for biomolecules.Figure optionsDownload as PowerPoint slide
Journal: Journal of Organometallic Chemistry - Volume 692, Issue 6, 15 February 2007, Pages 1363–1371