کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1328278 | 977559 | 2007 | 6 صفحه PDF | دانلود رایگان |
Dibromoborane–dimethyl sulfide (BHBr2–SMe2) displays high degrees of chemo- and regioselectivity during the brominative cleavage of the epoxy group into vicinal bromohydrins in the presence of alkene, alkyne, allene, ether, acetal and acetonide, besides its hydroborating ability. Several reducible functional groups, such as chloride, aldehyde, ketone, azide, ester, nitrile and tert-amino ester, have been successfully accommodated during the epoxide opening process.
Regio- and chemoselective cleavage of epoxides into β-bromohydrins utilizing the commercially available reagent, BHBr2–SMe2, is described. Several reactive and reducible functional groups, such as, alkene, alkyne, allene, ethers, acetal, ketal, chloride, aldehyde, ketone, azide, ester, nitrile and tert-amino ester, have been successfully accommodated during the epoxide opening reactions.Figure optionsDownload as PowerPoint slide
Journal: Journal of Organometallic Chemistry - Volume 692, Issue 7, 1 March 2007, Pages 1608–1613