Synthesis, crystal structure, and coordination properties of a helical peptide having β-(3-pyridyl)-l-alanine and l-glutamic acid residues

A novel helical peptide, Boc-Leu-Aib-Glu-Leu-Leu-Pal-Aib-Leu-OEt (1) (Boc = tert-butoxycarbonyl, Aib = 2-aminoisobutylic acid, Pal = β-(3-pyirdyl)-l-alanine) was synthesized and yielded fine crystals as an acetnitrile solvate. The metal ion binding properties of 1 were tested for CoCl2 using UV/vis, CD, Raman, and 1H NMR spectroscopies.