کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1328341 1499949 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Asymmetric hydrogenation of aromatic ketones using polymeric catalyst prepared from polymer-supported 1,2-diamine
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Asymmetric hydrogenation of aromatic ketones using polymeric catalyst prepared from polymer-supported 1,2-diamine
چکیده انگلیسی

tert-Butyloxycarbonyl (Boc) protected chiral 1,2-diamine monomers 3 were copolymerized with achiral vinyl monomers such as styrene, methacrylates, acrylates, methacrylamide, and acrylamide to give crosslinked polymers P2 containing chiral 1,2-diamine moieties. Deprotection of the Boc groups in the polymer afforded the crosslinked chiral 1,2-diamine polymer P3. The diamine polymer was allowed to react with RuCl2/BINAP in DMF to form polymeric complex. Asymmetric hydrogenation of aromatic ketones smoothly proceeded using the polymeric complex to give the corresponding secondary alcohol in quantitative yield with high level of enantioselectivity up to 98% ee in a mixed solvent of DMF and 2-propanol. The polymeric catalyst can be recycled several times without loss of the activity.

The polymer-supported chiral 1,2-diamines were synthesized by copolymerization of the chiral 1,2-diamine monomer and various kinds of achiral monomers. The asymmetric hydrogenation of aromatic ketones with polymer-supported catalyst prepared from the polymeric chiral 1,2-diamine ligand leads to the corresponding secondary alcohols in quantitative yield with high level of enantioselectivity.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Organometallic Chemistry - Volume 692, Issues 1–3, 1 January 2007, Pages 487–494
نویسندگان
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