Synthesis, structure, and hydrolytic reaction of trans-dichlorobis(diethanolamine-N)palladium(II) with N-acetylated L-histidylglycine dipeptide

The reaction of PdCl2, or K2PdCl4, with diethanolamine (DEA), in the molar ratio 1:2, affords the trans-[PdCl2(DEA)2] complex. X-ray structure analysis of this complex confirmed the formation of the trans-isomer. In the hydrolytic reaction between the trans-[PdCl2(DEA)2] or the trans-[Pd(H2O)2(DEA)2]2+ complex and MeCOHis-Gly dipeptide, cleavage of the amide bond involving the carboxylic group of histidine was observed.