Synthesis of 13C-labeled and functionalized Hyaluronan derivatives for biophysical studies and surface modifications

A convergent synthesis of a tetrasaccharide partial sequence of 13C-labeled Hyaluronan is presented. This tetrasaccharide can be used for biophysical studies as well as for surface modifications. Furthermore, tetrasaccharide 7 can be employed for the synthesis of additionally labeled higher oligomers of Hyaluronan on the basis of the presented methodology.

A convergent synthesis of 13C-labeled and non-labeled Hyaluronic acid tetrasaccharide for biophysical studies and surface modifications is presented.Figure optionsDownload as PowerPoint slide