کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1359052 | 981380 | 2010 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Novel antifungal agents: Triazolopyridines as inhibitors of β-1,6-glucan synthesis
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Novel antifungal agents: Triazolopyridines as inhibitors of β-1,6-glucan synthesis Novel antifungal agents: Triazolopyridines as inhibitors of β-1,6-glucan synthesis](/preview/png/1359052.png)
چکیده انگلیسی
Preparations and in vitro antifungal activities of triazolopyridines, imidazopyridines, and a pyrazolopyridine were reported. Among those scaffolds, triazolopyridine was found to be the specific inhibitor of the synthesis of β-1,6-glucan, an essential component of the fungal cell wall, and to show potent antifungal activities against several Candida species.
Triazolopyridine was discovered as a promising scaffold for novel antifungal agents, inhibiting β-1,6-glucan synthesis.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 18, Issue 16, 15 August 2010, Pages 5845–5854
Journal: Bioorganic & Medicinal Chemistry - Volume 18, Issue 16, 15 August 2010, Pages 5845–5854
نویسندگان
Jun-ichi Kuroyanagi, Kazuo Kanai, Yuuichi Sugimoto, Tetsunori Fujisawa, Chikanori Morita, Takashi Suzuki, Katsuhiro Kawakami, Makoto Takemura,