کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1359498 1500521 2012 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Anti-infective and herbicidal activity of N-substituted 2-aminobenzothiazoles
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Anti-infective and herbicidal activity of N-substituted 2-aminobenzothiazoles
چکیده انگلیسی

In this study, a series of N-substituted 2-aminobenzothiazoles was prepared according to a recently developed method. Twelve compounds were tested for their activity related to the inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. Primary in vitro screening of the discussed compounds was also performed against fungal, bacterial and mycobacterial species. The biological activities of some compounds were comparable or higher than the standards phenoxymethylpenicillin or pyrazinamide. The most effective compounds demonstrated insignificant toxicity against the human monocytic leukemia THP-1 cell line. For all compounds, the structure-activity relationships are discussed.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 20, Issue 24, 15 December 2012, Pages 7059–7068
نویسندگان
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