کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1360802 981448 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Thiazole Orange derivatives: Synthesis, fluorescence properties, and labeling cancer cells
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Thiazole Orange derivatives: Synthesis, fluorescence properties, and labeling cancer cells
چکیده انگلیسی

A series of Thiazole Orange (TO) derivatives were synthesized and modified by introducing different substitutional groups on benzothiazole and 4-methylquinoline All the TO derivatives were confirmed by 1HNMR and MS. TO derivative bearing NH2– was modified by folic acid and used to label breast cancer cells. The phenomenon of fluorescence enhancement was shown by the fluorescence spectrums of TO derivatives and micrographs of the labeled breast cancer cells. It offered a new try in the aspect of labeling cells by the embedded dyes.

A series of Thiazole Orange (TO) derivatives were synthesized and modified. TO derivatives modified by folic acid were also studied and their preliminary labeling breast cancer cells was carried out.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 17, Issue 2, 15 January 2009, Pages 585–591
نویسندگان
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