Isosteric probes provide structural requirements essential for detoxification of the phytoalexin brassinin by the fungal pathogen Leptosphaeria maculans

Essential structural features of substrates of brassinin oxidase: (i) -NH at the (mono/dithio)carbamate, urea or thiourea group; (ii) methylene bridge between indole and functional group; (iii) methyl or ethyl group attached to Z group.