Potential antitumoral properties of a new copper complex with santonic acid

A new copper(II) complex of santonic acid [Cu2(sant)4(H2O)2]·212H2O has been prepared and characterized by electronic, vibrational, EPR spectral studies, and stability determinations in solution. The presence of two antiferrromagnetically coupled copper centers in the solid state was detected by EPR. The dinuclear Cu(II) complex crystallizes in the tetragonal P43212 space group, with a = b = 14.498(3), c = 64.07(1) Å. Biological studies indicate that the complex displays interesting potential antitumoral actions.

A new copper(II) complex of santonic acid [Cu2(sant)4(H2O)2]·212H2O was prepared and characterized. Proliferative and morphological assays on different cell lines indicate that the complex displays interesting potential antitumoral actions.Figure optionsDownload as PowerPoint slide