کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1361658 981469 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Small photoactivatable molecules for controlled fluorescence activation in living cells
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Small photoactivatable molecules for controlled fluorescence activation in living cells
چکیده انگلیسی

The search for chemical probes which allow a controlled fluorescence activation in living cells represent a major challenge in chemical biology. To be useful, such probes have to be specifically targeted to cellular proteins allowing thereof the analysis of dynamic aspects of this protein in its cellular environment. The present paper describes different methods which have been developed to control cellular fluorescence activation emphasizing the photochemical activation methods known to be orthogonal to most cellular components and, in addition, allowing a spatio-temporal controlled triggering of the fluorescent signal.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 19, Issue 3, 1 February 2011, Pages 1023–1029
نویسندگان
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