کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1363714 981520 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis of sialic acid derivatives having a CC double bond substituted at the C-5 position and their glycopolymers
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis of sialic acid derivatives having a CC double bond substituted at the C-5 position and their glycopolymers
چکیده انگلیسی

Glycomonomers of sialic acid in which the acetamide group at C-5 was converted into two kinds of CC double bond substituents were prepared and the fully protected glycomonomers were directly polymerized before deprotection steps. Radical polymerization with acrylamide in DMF in the presence of ammonium persulfate and N,N,N’,N’-tetramethylethylenediamine proceeded smoothly and gave corresponding sialopolymers. Interestingly glycomonomers had hemagglutination inhibitory activities not only for H1N1 but also for H3N2 of human influenza virus strains.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 19, Issue 17, 1 September 2009, Pages 5105–5108
نویسندگان
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