کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1364393 | 981535 | 2008 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Bacterial translation inhibitors, 1-acylindazol-3-ols as anthranilic acid mimics
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
The discovery and initial optimization of a novel anthranilic acid derived class of antibacterial agents has been described in a recent series of papers. This paper describes the discovery of 1-acylindazol-3-ols as a novel bioisostere of an anthranilic acid. The synthesis and structure–activity relationships of the indazol bioisosteres are described herein.
This paper describes the discovery of 1-acylindazol-3-ols as a novel bioisostere of an anthranilic acid. The synthesis and structure–activity relationships of the indazol bioisosteres are described herein.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 18, Issue 23, 1 December 2008, Pages 6293–6297
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 18, Issue 23, 1 December 2008, Pages 6293–6297
نویسندگان
Cory Stiff, David R. Graber, Atli Thorarensen, Brian D. Wakefield, Keith R. Marotti, Earline P. Melchior, Michael T. Sweeney, Fusen Han, Douglas C. Rohrer, Gary E. Zurenko, Donna L. Romero,