Synthesis and cytotoxicity of aurilide analogs

The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure–activity relationships were investigated.

The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure–activity relationships were investigated.Figure optionsDownload as PowerPoint slide