Binding of actinomycin C1 (D) and actinomin to base-modified oligonucleotide duplexes with parallel chain orientation

Actinomycin displaces the pre-bound ethidium bromide in anti-parallel DNA but not in parallel DNA, while actinomin leads to displacement in both DNA structures. Highly fluorescent ethidium bromide, Low fluorescent ethidium bromide, Actinomycin D, Actinomin.