Novel poly(ADP-ribose) polymerase-1 inhibitors

Synthesis and activity of a series of 4-thiazol-yl substituted analogs of novel pyrrolocarbazole 1 as poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors have been disclosed.

Synthesis and activity of a series of 4-thiazol-yl substituted analogs of a novel pyrrolocarbazole as poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors have been disclosed.Figure optionsDownload as PowerPoint slide