کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1367463 981635 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Structure–activity relationships of α-amino acid ligands for the α2δ subunit of voltage-gated calcium channels
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Structure–activity relationships of α-amino acid ligands for the α2δ subunit of voltage-gated calcium channels
چکیده انگلیسی

A series of α-amino acids were identified as ligands which compete with gabapentin for binding to the α2δ subunit of voltage-dependent Ca2+ channels. Potent analogs were identified. Their activity in an in vivo pain assay is described.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 5, 1 March 2006, Pages 1138–1141
نویسندگان
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