کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1369122 981746 2015 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis and antimicrobial activity of novel benzoxazine sulfonamide derivatives
ترجمه فارسی عنوان
سنتز و فعالیت ضد میکروبی مشتقات بنزوکسازین سولفونامید جدید
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
چکیده انگلیسی

A new series of benzoxazine-6-sulfonamide derivatives were synthesized in excellent yields and the resulting compounds were evaluated for their antimicrobial activities. All the synthesized compounds were assessed for their antibacterial and antifungal activities. Among them 1a, 1b, 1c, 1e, 1h, 2c, 2d, 2e, 2g, 2h, 2i, 2j, 2k and 2l showed low inhibitory concentration (MIC of 31.25 and 62.5 μg/mL) against Gram-positive bacteria, Gram-negative bacteria and fungi, which are comparable to the inhibitory effect of standard drugs.

Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 25, Issue 7, 1 April 2015, Pages 1643–1646
نویسندگان
, , , , , , ,