کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1370583 | 981823 | 2011 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Flavans from Iris tenuifolia and their effects on β-amyloid aggregation and neural stem cells proliferation in vitro
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Flavans from Iris tenuifolia and their effects on β-amyloid aggregation and neural stem cells proliferation in vitro Flavans from Iris tenuifolia and their effects on β-amyloid aggregation and neural stem cells proliferation in vitro](/preview/png/1370583.png)
چکیده انگلیسی
Two new flavans (1, 2) and a new flavanone (3), together with three known compounds (4–6), were isolated from the roots of Iris tenuifolia. Their structures were elucidated by means of spectroscopic methods including 1D and 2D NMR techniques and mass spectrometry. Compounds 1, 4, and 6 were further confirmed by single-crystal X-ray diffraction analysis. Biological evaluation showed that compounds 1 and 4 were positive in inhibiting β-amyloid (Aβ) aggregation and promoting neural stem cells (NSCs) proliferation, respectively.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 21, Issue 15, 1 August 2011, Pages 4400–4403
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 21, Issue 15, 1 August 2011, Pages 4400–4403
نویسندگان
Yan-Mei Cui, Hui Wang, Quan-Ru Liu, Mei Han, Yang Lu, Chang-Qi Zhao,