کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1370620 981823 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cytotoxic diterpenoid quinonemethides from the roots of Pygmacopremna herbacea
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Cytotoxic diterpenoid quinonemethides from the roots of Pygmacopremna herbacea
چکیده انگلیسی

Two new diterpenoid quinonemethides (1 and 2) along with two known compounds (3 and 4) were isolated from the hexane and ethyl acetate extracts of root nodules of Pygmacopremna herbacea. The structures of the new compounds were established by spectroscopic data interpretation. Single crystal X-ray diffraction analysis confirmed the structure of 1. The cytotoxic activities of these compounds were evaluated against A 549, HEPG2, MCF-7, PC-3 and HELA cancer cell lines. Compounds 4, 2 and 1 were shown very good cytotoxic activity.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 21, Issue 15, 1 August 2011, Pages 4581–4584
نویسندگان
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