A selective ‘Off–On’ fluorescent sensor for Zn2+ based on hydrazone–pyrene derivative and its application for imaging of intracellular Zn2+

A simple and effective fluorescent sensor based on hydrazone–pyrene has been synthesized. This probe displays a highly selective fluorescent enhancement with Zn2+, and application of this probe to detect the intrinsic Zn2+ ions present in pancreatic β-cells was successfully demonstrated.

Fluorescent probe 1 displays a highly selective fluorescent enhancement with Zn2+, and application of this probe to detect the intrinsic Zn2+ ions present in pancreatic β-cells was demonstrated.Figure optionsDownload as PowerPoint slide