کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1373223 | 981893 | 2007 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The discovery of indole-derived long acting β2-adrenoceptor agonists for the treatment of asthma and COPD
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The discovery of indole-derived long acting β2-adrenoceptor agonists for the treatment of asthma and COPD The discovery of indole-derived long acting β2-adrenoceptor agonists for the treatment of asthma and COPD](/preview/png/1373223.png)
چکیده انگلیسی
The design and profile of a series of indole containing long acting β2-adrenoceptor agonists is described. Evaluation of these analogues using an in vitro guinea pig trachea tissue model demonstrates that analogues within this series have salmeterol-like duration of action with potential for long duration of action in humans.
The design and profile of a series of indole containing long acting β2-adrenoceptor agonists is described. Evaluation of these analogues using an in vitro guinea pig trachea tissue model demonstrates that analogues within this series have salmeterol-like duration of action with potential for long duration of action in humans.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 17, Issue 22, 15 November 2007, Pages 6188–6191
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 17, Issue 22, 15 November 2007, Pages 6188–6191
نویسندگان
Alan D. Brown, Mark E. Bunnage, Paul A. Glossop, Mark Holbrook, Rhys D. Jones, Charlotte A.L. Lane, Russell A. Lewthwaite, Simon Mantell, Christelle Perros-Huguet, David A. Price, Rob Webster,