کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1373732 | 981905 | 2009 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis of novel cholesterol-based cationic lipids for gene delivery
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis of novel cholesterol-based cationic lipids for gene delivery Synthesis of novel cholesterol-based cationic lipids for gene delivery](/preview/png/1373732.png)
چکیده انگلیسی
The new cholesterol-based cationic lipids B, C, and D with an ether linked spacer were synthesized by using aminopropyl chain extension with acrylonitrile. The cholesterol-based cationic lipid A with carbamoyl linkage were also synthesized in order to compare the difference in transfection efficiency of the two linkage types. To this end, GFP expression of these cationic lipids was confirmed respectively.
The development of optimum cationic lipids for cationic liposome delivery systems.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 19, Issue 11, 1 June 2009, Pages 2986–2989
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 19, Issue 11, 1 June 2009, Pages 2986–2989
نویسندگان
Bieong-Kil Kim, Kyung-Oh Doh, Joo Hyeung Nam, Hyungu Kang, Jong-Gu Park, Ik-Jae Moon, Young-Bae Seu,