کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1374777 | 981924 | 2008 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Identification of small molecule agonists of the motilin receptor Identification of small molecule agonists of the motilin receptor](/preview/png/1374777.png)
High-throughput screening resulted in the identification of a series of novel motilin receptor agonists with relatively low molecular weights. The series originated from an array of biphenyl derivatives designed to target 7-transmembrane (7-TM) receptors. Further investigation of the structure–activity relationship within the series resulted in the identification of compound (22) as a potent and selective agonist at the motilin receptor.
High-throughput screening resulted in the identification of a series of novel motilin receptor agonists with relatively low molecular weights. The series originated from an array of biphenyl derivatives designed to target 7-transmembrane (7-TM) receptors. Further investigation of the structure–activity relationship within the series resulted in the identification of compound (22) as a potent and selective agonist at the motilin receptor.Figure optionsDownload as PowerPoint slide
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 18, Issue 24, 15 December 2008, Pages 6423–6428