کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1375178 | 981933 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and antifungal activity of 6-hydroxycinnolines
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis and antifungal activity of 6-hydroxycinnolines Synthesis and antifungal activity of 6-hydroxycinnolines](/preview/png/1375178.png)
چکیده انگلیسی
6-Hydroxycinnolines 2 and cyclohexa-2,5-diene-1,4-dione derivatives 6 were synthesized and tested for in vitro antifungal activity against Candida and Aspergillus species. 6-Hydroxycinnolines 2 showed, in general, more potent antifungal activity against Candida species than the other cyclohexa-2,5-diene-1,4-diones. The results suggest that 6-hydroxycinnolines would be potent antifungal agents.
6-Hydroxycinnolines and cyclohexa-2,5-diene-1,4-dione derivatives were synthesized and tested for in vitro antifungal activity against Candida species and Aspergillus niger. Among them, 2-amino-7,8-dimethyl-6-hydroxycinnolines exhibited potent antifungal activity.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 7, 1 April 2006, Pages 1850–1853
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 7, 1 April 2006, Pages 1850–1853
نویسندگان
Chung-Kyu Ryu, Jung Yoon Lee,