Effect of the oligo(ethylene glycol) group on the antioxidant activity of manganese salen complexes

The synthesis and antioxidant activity of oligo(ethylene glycol)-modified manganese salen complexes are reported. Their SOD activities were similar and 2- to 3-fold more potent than the standard compound EUK-134. Their catalase-like activity was lower than that of EUK-134 in the initial conversion rate; however, some analogs exhibited a better catalytic turnover number.

The SOD activities of oligo(ethylene glycol) derivatives of manganese salen complexes were similar and slightly more potent than the standard compound EUK-134. Their catalase-like activity was lower than that of EUK-134 in the initial conversion rate; however, some analogs exhibited a better catalytic turnover number.Figure optionsDownload as PowerPoint slide