کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1377321 | 981976 | 2008 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and in vitro anti-leukemic activity of structural analogues of JS-K, an anti-cancer lead compound
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis and in vitro anti-leukemic activity of structural analogues of JS-K, an anti-cancer lead compound Synthesis and in vitro anti-leukemic activity of structural analogues of JS-K, an anti-cancer lead compound](/preview/png/1377321.png)
چکیده انگلیسی
Structural analogues of JS-K, an anti-cancer lead compound, were prepared and their in vitro anti-leukemic activity was determined. The rate of nitric oxide release from the corresponding diazeniumdiolate anions did not appear to affect the anti-leukemic activity of the prodrug forms. Two compounds with potent inhibitory activity and a potentially favorable toxicological profile were identified.
Synthesis and anti-leukemic activity of structural analogues of JS-K, an anti-cancer lead compound, are reported.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 18, Issue 3, 1 February 2008, Pages 950–953
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 18, Issue 3, 1 February 2008, Pages 950–953
نویسندگان
Harinath Chakrapani, Michael M. Goodblatt, Vidya Udupi, Swati Malaviya, Paul J. Shami, Larry K. Keefer, Joseph E. Saavedra,