کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1377394 981977 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Identification of a novel series of benzimidazoles as potent and selective antagonists of the human melanocortin-4 receptor
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Identification of a novel series of benzimidazoles as potent and selective antagonists of the human melanocortin-4 receptor
چکیده انگلیسی

A novel series of benzimidazoles was identified and optimized, leading to the discovery of potent and selective antagonists of the human melanocortin-4 receptor. In addition, compound 5i was shown to cross the blood–brain barrier after intravenous dosing in rats.

A novel series of benzimidazoles was identified and optimized, leading to the discovery of potent and selective antagonists of the human melanocortin-4 receptor. In addition, compound 5i was shown to cross the blood–brain barrier after intravenous dosing in rats.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 17, Issue 16, 15 August 2007, Pages 4464–4470
نویسندگان
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