کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1377406 981977 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis and antibacterial activity of novel fluoroquinolones containing substituted piperidines
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis and antibacterial activity of novel fluoroquinolones containing substituted piperidines
چکیده انگلیسی

The design and synthesis of new fluoroquinolone antibacterial agents having substituted piperidine rings at the C-7 position are described. Most of the new compounds demonstrated high in vitro antibacterial activity. Several of them exhibited significant activities against Gram-positive organisms, which were more potent than those of gemifloxacin, Linezolid, and vancomycin.

The design, synthesis, and antibacterial activity of new fluoroquinolones possessing substituted piperidine rings at the C-7 position are described.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 17, Issue 16, 15 August 2007, Pages 4523–4526
نویسندگان
, , , ,