Design and synthesis of a biotin-tagged photoaffinity probe of paeoniflorin

A trifunctional probe (binding element–photoreactive group–affinity tag) of natural product paeoniflorin was designed and synthesized based on the previous primary structure-activity relationship. This new probe is a potential tool for labeling, purification, and identification of the target proteins.

A trifunctional biotin-tagged photoaffinity probe of paeoniflorin was designed and synthesized, and this new biotinylated probe is a potential tool for labeling, purification, and identification of the target proteins.Figure optionsDownload as PowerPoint slide