Keywords: Paeoniflorin; HPLC-MS/MS; Metabolism; Human intestinal microflora;
مقالات ISI (ترجمه نشده)
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Keywords: Paeoniflorin; Paeonol; Ionic liquid; Microwave irradiation; Distillation and simultaneous extraction;
Keywords: AA; Angelica Archangelica; AGNHW; AnGongNiuHuang Wan; AM; Astragalus membranaceus; AMP; adenosine monophosphate; AMPK; adenosine 5â²-monophosphate activated protein kinase; Ang II; angiotensin II; AP; Astragalus polysaccharide; ASIV; astragaloside IV; AS
Keywords: Albiflorin; Paeoniflorin; Chemotherapy; Myelosuppression
Paeoniflorin attenuates depressive behaviors in systemic lupus erythematosus mice
Keywords: Paeoniflorin; Systemic lupus erythematosus; Depressive behaviors;
Paeoniflorin inhibits Rho kinase activation in joint synovial tissues of rats with collagen-induced rheumatoid arthritis
Keywords: Paeoniflorin; Rheumatoid arthritis; Rho kinase; Synovial tissue;
Beneficial effects of paeoniflorin on osteoporosis induced by high-carbohydrate, high-fat diet-associated hyperlipidemia in vivo
Keywords: Paeoniflorin; Hyperlipidemia; Osteoporosis; Bone remodeling;
Paeoniflorin augments systemic Candida albicans infection through inhibiting Th1 and Th17 cell expression in a mouse model
Keywords: Paeoniflorin; Candida albicans; Fluconazole; T helper cells;
Paeoniflorin inhibits VSMCs proliferation and migration by arresting cell cycle and activating HO-1 through MAPKs and NF-κB pathway
Keywords: Paeoniflorin; Vascular smooth muscle cell; Proliferation; Migration; Atherosclerosis; Inflammation;
Simultaneous UPLC-MS/MS determination of four components of Socheongryong-tang tablet in human plasma: Application to pharmacokinetic study
Keywords: Schizandrin; Ephedrine; Paeoniflorin; Cinnamic acid; UPLC-MS/MS; Socheongryong-tang;
Chemical markers for quality control of bran-fried sulfur-fumigated Paeoniae Radix Alba
Keywords: Bran-fried Paeoniae Radix Alba; Sulfur fumigation; Chemical markers; Sulfur dioxide residue; Paeoniflorin; Paeoniflorin sulfonate;
Paeoniflorin inhibits activation of the IRAK1-NF-κB signaling pathway in peritoneal macrophages from lupus-prone MRL/lpr mice
Keywords: Paeoniflorin; Systemic lupus erythematosus; IRAK1; NF-κB;
Nuciferine and paeoniflorin can be quality markers of Tangzhiqing tablet, a Chinese traditional patent medicine, based on the qualitative, quantitative and dose-exposure-response analysis
Keywords: Tangzhiqing tablet (TZQ); Quality markers (Q-marker); Nuciferine; Paeoniflorin; Dose-exposure-response; LC-MS/MS; liquid chromatography combined with tandem mass spectrometry; Q-marker; Quality marker; Q-TOF/MS; quadrupole time-of-flight mass spectromet
Identify super quality markers from prototype-based pharmacokinetic markers of Tangzhiqing tablet (TZQ) based on in vitro dissolution/ permeation and in vivo absorption correlations
Keywords: Tangzhiqing tablet (TZQ); Quality marker (Q-marker); Pharmacokinetic marker (PK-marker); Nuciferine; Paeoniflorin; In vitro-in vivo correlation (IVIVC); CHM; Chinese herbal medicine; DDASS; drug dissolution/ absorption simulating system; IVIVC; in vitro-i
Paeoniflorin reduces neomycin-induced ototoxicity in hair cells by suppression of reactive oxygen species generation and extracellularly regulated kinase signalization
Keywords: Neomycin; Paeoniflorin; ROS; MAPK; Ototoxicity; Apoptosis;
Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells
Keywords: Chinese herbal medicine; Paeonia suffruticosa; Pancreatic cancer; Proteostasis; Autophagy; Apoptosis; 5GG; penta-O-galloyl-β-D-glucose hydrate; CHM; Chinese herbal medicine; DCFDA; 2â²-7â²-dichlorofluorescin diacetate; EGFR; epidermal growth factor rec
Neuroprotective effect of paeoniflorin on okadaic acid-induced tau hyperphosphorylation via calpain/Akt/GSK-3β pathway in SH-SY5Y cells
Keywords: PF; paeoniflorin; OA; okadaic acid; 3-MA; 3-methyladenine; Rapa; rapamycin; LiCl; lithium chloride; AD; Alzhiemer's disease; CAST; Ac-calpastain; CQ; chloroquine; NFTs; neurofibrillary tangles; CaMKII; calcium/calmodulin protein kinase II; MAP2; microtu
Induction of suppressor of cytokine signaling 3 via HSF-1-HSP70-TLR4 axis attenuates neuroinflammation and ameliorates postoperative pain
Keywords: HSP70; TLR4; SOCS3; Inflammation tolerance; Paeoniflorin; Postoperative pain;
Paeoniflorin suppressed IL-22 via p38 MAPK pathway and exerts anti-psoriatic effect
Keywords: Paeoniflorin; Psoriasis; IL-22; p38 MARK;
Prophylactic topical paeoniflorin prevents mechanical allodynia caused by paclitaxel in mice through adenosine A1 receptors
Keywords: Paeoniflorin; Paclitaxel; Allodynia; Adenosine A1 receptor; PTX; paclitaxel; PF; paeoniflorin; CHOP; C/EBP homologous protein; ER; endoplasmic reticulum; A1R; adenosine A1 receptor; DPCPX; 8-cyclopentyl-1,3-diprooylxanrhine; GAPDH; glyceraldehyde 3-phosph
Paeoniflorin suppresses lipid accumulation and alleviates insulin resistance by regulating the Rho kinase/IRS-1 pathway in palmitate-induced HepG2Cells
Keywords: Paeoniflorin; Lipid accumulation; Insulin resistance; Rho kinase;
Paeoniflorin ameliorates cognitive dysfunction via regulating SOCS2/IRS-1 pathway in diabetic rats
Keywords: Paeoniflorin; Diabetes; Cognitive dysfunction; SOCS2/IRS-1; Tau phosphorylation; Akt; protein kinase B; DE; diabetic encephalopathy; DM; diabetes mellitus; GSK-3β; glycogen synthase kinase-3β; IL-1β; interleukin-1β; IRS-1; insulin receptor substrate-1
Neuroprotection by Paeoniflorin in the MPTP mouse model of Parkinson's disease
Keywords: Parkinson's disease; Paeoniflorin; Neuroprotective effect; Phosphatidylinositol 3-kinase (PI3K)/Akt;
Protective effects of paeoniflorin on TNBS-induced ulcerative colitis through inhibiting NF-kappaB pathway and apoptosis in mice
Keywords: Paeoniflorin; Ulcerative colitis; NF-kappaB pathway; Apoptosis;
Paeoniflorin and liquiritin, two major constituents in Chinese herbal formulas used to treat hyperprolactinemia-associated disorders, inhibits prolactin secretion in prolactinoma cells by different mechanisms
Keywords: D2R; dopamine D2 receptors; MCP; metoclopramide; TGF; transforming growth factor; TNF; tumor necrosis factor; YRTJ; Yiru Tiaojing; Dopamine D2 receptor; Hyperprolactinemia; Paeoniflorin;
Paeoniflorin ameliorates Adriamycin-induced nephrotic syndrome through the PPARγ/ANGPTL4 pathway in vivo and vitro
Keywords: PF; paeoniflorin; NS; nephrotic syndrome; ADR; adriamycin; PPARγ; peroxisome proliferator-activated receptor gamma; ANGPTL4; angiopointin-like 4; HE; hematoxylin-eosin; Scr; Serum creatinine; TG; triglycerides; TP; serum total protein; ALB; serum albumin
Protective effects of Paeoniflorin against AOPP-induced oxidative injury in HUVECs by blocking the ROS-HIF-1α/VEGF pathway
Keywords: Paeoniflorin; AOPPs; Reactive oxygen species; HIF-1α; VEGF; AOPPs; advanced oxidation protein products; HUVECs; human umbilical vein endothelial cells; DCFH-DA; dichlorofluorescein-diacetate; ROS; reactive oxygen species; MMP; mitochondrial membrane pote
New analytical method for determination of epimer metabolites in rat plasma after oral administration of Paeoniflorin by UPLC-TOF-MS following picolinoyl derivatization
Keywords: Paeoniflorin; Metabolite; Derivatization;
Paeoniflorin targets apoptosis and ameliorates fibrosis in murine schistosomiasis mansoni: A novel insight
Keywords: Schistosomiasis; Paeoniflorin; Praziquantel; Caspase-3; P53; NF-kB; TGF-β1; α-SMA; IL-13;
Paeoniflorin inhibits proliferation and invasion of breast cancer cells through suppressing Notch-1 signaling pathway
Keywords: Paeoniflorin; Breast cancer; Proliferation; Invasion; Notch-1
Paeoniflorin attenuates cardiac dysfunction in endotoxemic mice via the inhibition of nuclear factor-κB
Keywords: Paeoniflorin; Cardiac dysfunction; Endotoxin; Phosphatidlyinositide 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway
Unique immunomodulatory effect of paeoniflorin on type I and II macrophages activities
Keywords: Paeoniflorin; M1 macrophage; M2 macrophage; Autoimmune and autoinflammatory diseases
Pharmacokinetics and pharmacodynamics of glycyrrhetinic acid with Paeoniflorin after transdermal administration in dysmenorrhea model mice
Keywords: Glycyrrhetinic acid; Paeoniflorin; Pharmacokinetics; Pharmacodynamics; Analgesic; Transdermal drug deliveryPLD, Chinese peony-Liquorice Decoction; GA, glycyrrhetinic acid; PF, paeoniflorin; TTS, transdermal therapeutic system; PK, pharmacokinetics; PD, ph
Paeoniflorin suppresses IL-6/Stat3 pathway via upregulation of Socs3 in dendritic cells in response to 1-chloro-2,4-dinitrobenze
Keywords: Paeoniflorin; Allergic contact dermatitis; Dendritic cells; Th17 cells; Suppressor of cytokine signaling (Socs);
Paeoniflorin ameliorates symptoms of experimental Sjogren's syndrome associated with down-regulating Cyr61 expression
Keywords: Paeoniflorin; Sjogren's syndrome; Cyr61/CCN1; Epithelial cells
Pharmacokinetics, Safety, and Tolerability of Amygdalin and Paeoniflorin After Single and Multiple Intravenous Infusions of Huoxue-Tongluo Lyophilized Powder for Injection in Healthy Chinese Volunteers
Keywords: amygdalin; clinical trial; LC-MS/MS; paeoniflorin; pharmacokinetic properties;
Immunopharmacology and inflammationPaeoniflorin inhibits imiquimod-induced psoriasis in mice by regulating Th17 cell response and cytokine secretion
Keywords: Paeoniflorin; Psoriasis; Imiquimod; Th17; Cytokine secretion;
CP-25 attenuates the inflammatory response of fibroblast-like synoviocytes co-cultured with BAFF-activated CD4+ T cells
Keywords: RA; rheumatoid arthritis; FLS; fibroblast-like synoviocytes; BAFF; B cell activating factor belonging to the TNF family; TACI; transmembrane activator and calcium modulator and cyclophilin ligand interactor; BCMA; B-cell maturation antigen; BAFF-R; BAFF r
Production of paeoniflorin and albiflorin by callus tissue culture of Paeonia lactiflora Pall
Keywords: Albiflorin; Paeoniflorin; Callus; Plant cell cultures; Paeonia lactiflora Pall
Paeoniflorin down-regulates ATP-induced inflammatory cytokine production and P2X7R expression on peripheral blood mononuclear cells from patients with primary Sjögren's syndrome
Keywords: Paeoniflorin; P2X7 receptor; IL-6; IL-1β; Primary Sjögren's syndrome
Paeoniflorin attenuates allergic inflammation in asthmatic mice
Keywords: Paeoniflorin; Asthma; IL-5; IL-13; IL-17; MAPK
Paeoniflorin diminishes ConA-induced IL-8 production in primary human hepatic sinusoidal endothelial cells in the involvement of ERK1/2 and Akt phosphorylation
Keywords: Paeoniflorin; Hepatic sinusoidal endothelial cells; Concanavalin A; Interleukin-8;
Paeoniflorin protects against concanavalin A-induced hepatitis in mice
Keywords: Paeoniflorin; Concanavalin A; Hepatitis; Lymphocyte; TLR4; NF-κB
Paeoniflorin inhibits skin lesions in imiquimod-induced psoriasis-like mice by downregulating inflammation
Keywords: TGP; total glucosides of paeony; PF; paeoniflorin; RA; rheumatoid arthritis; SS; Sjögren's syndrome; SLE; systemic lupus erythematosus; CIA; collagen-induced arthritis; NOD; non-obese diabetic; IMQ; imiquimod; iNOS; inducible nitric oxide synthase; MIP-2
Oral administration of paeoniflorin attenuates allergic contact dermatitis by inhibiting dendritic cell migration and Th1 and Th17 differentiation in a mouse model
Keywords: DCs, dendritic cells; LCs, Langerhans cells; ACD, allergic contact dermatitis; DNCB, 1-chloro-2,4-dinitrobenzene; PF, paeoniflorinAllergic contact dermatitis; Paeoniflorin; 1-chloro-2,4-dinitrobenzene; Contact sensitivity; Dendritic cells
Influence of puerarin, paeoniflorin, and menthol on structure and barrier function of tight junctions in MDCK and MDCK-MDR1 Cells
Keywords: Puerarin; Paeoniflorin; Menthol; Tight junctions; Blood–brain barrier
Paeoniflorin selectively inhibits LPS-provoked B-cell function
Keywords: B cell; Paeoniflorin; LPS; CD40/CD40L; IL-4
Research ReportPaeoniflorin attenuates Aβ1-42-induced inflammation and chemotaxis of microglia in vitro and inhibits NF-κB- and VEGF/Flt-1 signaling pathways
Keywords: Aβ; beta-amyloid; AD; Alzheimer׳s disease; CNS; central nervous system; PF; paeoniflorin; TNF-α; tumor necrosis factor α; IL-1β; interleukin 1β; IL-6; interleukin 6; NF-κB p65; nuclear factor kappa B subunit p65; IκBα; NF-κB inhibitor alpha; CXC
A sensitive LC–MS/MS method for simultaneous determination of amygdalin and paeoniflorin in human plasma and its application
Keywords: Amygdalin; Paeoniflorin; Huoxue-Tongluo lyophilized powder for injection; LC–MS/MS; Pharmacokinetics
ZnSe quantum dots based fluorescence quenching method for determination of paeoniflorin
Keywords: ZnSe quantum dots; Paeoniflorin; Fluorescence intensity; Quenching;