Membrane permeable esterase-activated fluorescent imaging probe

An esterase-triggered probe 2 derived from a cyanine-based pH sensitive dye was developed for cell labeling. Permeation of probe 2 into cells and subsequent hydrolytic activation by cellular esterases result in a bright fluorescent intracellular signal.

An esterase-triggered probe 2 derived from a cyanine-based pH sensitive dye was developed for cell labeling.Figure optionsDownload as PowerPoint slide